research.
Preconception Hypoglycemia May Result in Negative Pregnancy Outcomes
A new study suggested that low blood sugar in women before conceiving led to a higher chance of certain adverse pregnancy outcomes. The risks include preterm birth, low birth weight, or birth defects. The study involved data from over 4,7 million Chinese women planning to conceive.
Salmon Nasal Cartilage Might Reduce Signs of Aging
A study evaluated the effect of Shanghai Huiwen Biotech Co.’s salmon nasal cartilage-derived proteoglycans powder (PG) on skin health. Subjects, taking daily PG supplementation of 20 mg, were reported to show improvements in skin elasticity and hydration, with reduced skin roughness and wrinkles, and decreased melanin content and brown spots.
Folate Linked to Slower Biological Age
A new study focused on determining associations of epigenetic biomarkers with one-carbon metabolism, a biochemical pathway essential in aging-related physiological processes. The researchers found a link between increased serum folate (promoter of one-carbon metabolism) and lower epigenetic age deviation. In contrast, higher levels of homocysteine (an indicator of one-carbon metabolism deficiencies) were connected to a higher epigenetic age deviation.
L. paracasei Could Improve Metabolic Health
A newly published trial suggested that L. paracasei NB23 probiotic supplementation could improve multiple markers of metabolic and muscle health, systolic and diastolic blood pressure, LDL/HDL ratio, HOMA-IR, and inflammatory cytokines. The results also showed an increase in muscle mass and lower limb strength among participants with no regular exercise habits.
Beta-Glucans May Enhance Vaccine Effect
A new study showed that supplementation with yeast beta-glucans, alongside receiving the flu vaccine, could enhance the number of antibodies, suggesting a better immune response to vaccination. In the beta-glucan group, 96% of participants had seroprotection, a measure of the immune response, compared to 84% in the placebo group.
Supplements Might Protect Skin from UV Damage
A recently published systematic review examined the evidence supporting the ability of certain supplements to reduce photoaging. According to the review, polyphenols and collagen-based supplements showed an improvement in the skin’s elasticity, while flavanols enhanced the minimal erythema dose, an indicator of the skin’s ability to combat photoaging.
Benicaros® Supports Gut Health in Dogs
A new in-vitro study on NutriLead’s prebiotic Benicaros® revealed that the active ingredient supported the production of beneficial short-chain fatty acids and stimulated Phocaeicola vulgatus bacterium in the canine gut. These effects are said to be consistent across 18 different dog donors studied, regardless of breed, size, or baseline microbiota.
Zenroot™ Shows High Bioavailability at Low Dose
OminActive’s proprietary brand of ashwaganda Zenroot™ showed higher plasma concentrations of withanolides at a lower dose compared to two other commercial products, according to a new study. The results also showed a higher absorption of Zenroot™ in the body.
Widespread Musculoskeletal Pain in Young Athletes
In a new study, over half of physically active youngsters had been diagnosed with growing pains, which could be a result of muscle overuse and structural abnormalities. The study also emphasized the importance of early nutritional education, noting unhealthy dietary habits among participants with pain compared to those without pain.
Study Highlights the Gut-Joint Axis Function
A recent study on the butyrate-producing bacterium E. rectale highlighted the function of the gut-joint axis. The results suggested E. rectale may exhibit a positive effect on rheumatoid arthritis in mice, leading to improvements in joint inflammation, bone health, and increased number of immune cells.
Ergothioneine Could Support Brain Health
Supplementation with Blue California’s ErgoActive® ergothioneine ingredient could improve subjective memory and sleep, according to a new study. Carried out on participants between the ages of 55 and 79 with a higher risk of cognitive decline, the study found a dose-dependent improvement in their subjective prospective memory and ability to fall asleep.
Curcumin May Support Oral Health
A new systematic review of seven studies found that curcumin formulations could improve various oral health conditions, such as periodontitis, gingivitis, and oral mucositis. The reviewed studies indicate that curcumin decreases inflammation, improves healing, and reduces patient discomfort.
Paprika Improves Oxygen Delivery to Vital Organs
New research on Glico Nutrition’s branded extract paprika xanthophyll (PX) demonstrated optimized quality of oxygen delivery in participants taking PX supplementation. This resulted in improved physical performance, attention, focus, and cognitive flexibility.
Dompé May Lower Cholesterol
Dompé Farmaceutici’s nutraceutical combination Cardioritmon Colesterolo® may help reduce both LDL and total cholesterol, according to a new study. The supplement includes actives such as berberine extract, SelectSIEVE OptiChol™ (olive fruit polyphenols), and Ritmon Colesystem® (sunflower seeds phytosterols). An average 4-7% reduction in LDL and 5-8% reduction in total cholesterol were observed.
Clasado’s Prebiotic Effective at Very Low Dose
New research on Clasado Biosciences’ Bimuno® GOS prebiotic demonstrated that the ingredient delivers a bifidogenic effect at a very low dose (380 mg of active GOS per day). This result could present an important development for formatting compact or multi-ingredient formats, such as capsules or tablets.
Review Discusses Potential of Vaginal Microbiome Diagnostics
A multi-institutional paper shines a light on the “untapped potential” of the vaginal microbiome in women’s health. Specifically, microbiome testing could have the potential to advance women’s health by providing better, personalized diagnosis and treatment. The author calls for increased investment in women’s health research.
More Interesting Studies:
- Two studies on saffron extract Safr’Inside™ showed that the active may reduce insomnia symptoms in healthy middle-aged adults and improve overall sleep quality in older adults with sleep complaints.
- A new trial on pear extract UPhenon® suggested that supplementation with the ingredient may reduce obesity without adverse effects.
- A study on kiwifruit extract Phloe® showed the extract might improve bowel habits and abdominal pain.
- A new study on cucumber extract Q-actin™ suggested the active’s potential for improving mood, sleep quality, and anxiety.
- A clinical study on ashwaganda ingredient Zenroot™ suggested that supplementation with this ingredient might result in reduced stress and improvements in mood, sleep quality, and occasional anxiety.




