research.
Arginine Might Reduce Alzheimer’s Disease Markers
Researchers found that oral arginine, a naturally occurring amino acid, may reduce amyloid β plaque formation, a precursor to Alzheimer’s disease, in vitro and in vivo. Supplementation with arginine demonstrated broader neuroprotective and anti-inflammatory effects as well.
NAD+ Might Protect Brain from Degenerative Effects of Alzheimer’s Disease
Researchers found that boosting NAD+ may help protect the brain from the degenerative effects of Alzheimer’s disease. NAD+ supplementation benefits have been validated in animal models, demonstrating improved RNA splicing, restored brain function, and enhanced memory performance.
Botanical NAD+ Booster Could Outperform Category’s Benchmark Nicotinamide Riboside
A new clinical trial on NXT USA’s BluNADBooster®, a natural NAD+ booster and polyphenol-rich healthy aging supplement, demonstrated that this botanical complex could improve key biomarkers of mitochondrial health, energy metabolism, inflammation, cognition, physical performance, and quality of life scores. Furthermore, a head-to-head study compared BluNADBooster® to the NAD+ precursor benchmark ingredient, Tru Niagen® nicotinamide riboside. The BluNADBooster® ingredient outperformed Tru Niagen®, while the blend of both ingredients performed the best.
Wheat Extract Could Enhance Hair and Skin Health in Men
A new consumer test study showed that Seppic’s CERAMOSIDES™, a wheat lipidic extract rich in phytoceramides, could enhance hair and skin health. The key study highlights revealed that 75% of men globally reported being satisfied with the anti-hair loss results. After 3 months, self-confidence scores related to hair loss improved by 11%, and the skin hydration score improved by 25%.
Early-Life Iron Deficiency May Pose Long-Term Impact on Immune Cells
New research showed that iron deficiency early in life can permanently impair the ability of lung memory T cells to produce vital infection-fighting proteins, even after iron levels are restored. This defect means that the immunological “memory” formed during iron deficiency may not provide adequate protection against future viral infections. The study highlights the crucial importance of ensuring children receive sufficient dietary iron for the proper development of their immune system.
Multivitamins Could Offer Blood Pressure Benefits
A secondary analysis of data from the COcoa Supplement & Multivitamin Outcomes Study (COSMOS) suggested long-term multivitamin supplementation could reduce hypertension risk and blood pressure in certain groups of older adults. The multivitamin group that received Haleon’s Centrum Silver demonstrated lowered hypertension risk in participants with comparatively lower diet quality and in participants with normal blood pressure at baseline.
Pro, Postbiotic Might Relieve Common Cold
A systematic review of eight trials suggested that daily intake of Kirin’s IMMUSE® (LC-Plasma), either live or heat-killed Lactococcus lactis strain, could help reduce cold-like symptoms. The analysis showed that LC-Plasma activated plasmacytoid dendritic immune cells and reduced symptoms such as cough and fever compared to placebo.
Probiotic Mix Could Support Respiratory Infection Recovery in Children
A new study on AB-Biotics and Kaneka Probiotics’ AB21®, a blend of four probiotic strains, found that this combination may reduce upper respiratory tract infection symptom duration in children. The results showed a shortened duration of fever by 40% (1,1 days) and pain/discomfort by 19% (0,7 days) compared to placebo. AB21® is formulated with Lactiplantibacillus plantarum KABP-033, L. plantarum KABP-022, L. plantarum KABP-023, and Pediococcus acidilactici KABP-021.
Nerve-Gut Axis May Lower Allergy Risk
A new study discovered that the intestinal nervous system might regulate the intestinal barrier, which is responsible for allergies. Researchers suggest that this nerve-gut axis is vital for digestion and maintaining barrier integrity by releasing the vasoactive intestinal peptide (VIP), a molecule that controls stem cell development in the intestinal wall. Without VIP, tuft cells can overgrow and trigger similar responses to allergens.
Pine Bark Extract Might Relieve Lipedema Symptoms in Women
A new clinical study showed that ingredient Pycnogenol®, a natural plant extract from the bark of the French maritime pine tree, could relieve the symptoms of lipedema, reduce body fat, and improve self-esteem associated with the condition. Pycnogenol® demonstrated relief across all reported symptoms, such as swelling of the legs, heavy legs, tenderness, and bruising. Additionally, the active group experienced an 8% reduction in body fat compared to placebo after 60 days of supplementation.
Vitamin C Might Boost Skin Collagen Production
Vitamin C intake could directly influence collagen production and skin renewal, according to a new study. Researchers found that skin absorbs vitamin C from the bloodstream more effectively than through topical products. The active group that consumed two vitamin C-rich Zespri™ SunGold™ kiwifruit daily saw improved skin structure, collagen formation, and epidermal renewal.
Fish Peptide Could Benefit Cognitive Health
Researchers found that a novel peptide from round scad, Pro-Pro-Trp (PPW), could support cognitive function. The results of molecular simulations, both in cellular models and in vivo experiments, showed that PPW provided neuroprotection in glutamate-damaged SH-SY5Y cells, attenuated cognitive decline in sleep-deprived mice, and alleviated oxidative stress and neuroinflammation.
Study Supports Creatine Safety in Female Soccer Players
A new study demonstrated that daily consumption of Alzhem’s Creavitalis® creatine monohydrate during an eight-month soccer season was not associated with any clinically significant biochemical changes in female soccer players. Data of 71 females, who initially received 20 g and later 5 g of Creavitalis® daily, showed no adverse effects on kidney or liver function.
Botanical Blend Might Support Weight Management
A recent consumer study, pending publication, suggested that Monteloeder’s Metabolaid®, a lemon verbena and hibiscus botanical blend, may help users manage cravings, emotional eating, and motivation, alongside modest weight reduction of around 3%. Participants also reported higher energy, and more than 70% noted better control and healthier food choices.
Scientists Establish Unified Measures for Gut Microbiome Health
ZOE’s scientists presented a new method for measuring an individual’s gut microbiome health, claimed to be the first reliable, repeatable, and globally applicable approach. This scientific analysis presented a global ranking of microbes by analyzing over 34.000 microbiomes, with results linking beneficial microbes to health outcomes. Healthy individuals might carry around 3,6-times more of these beneficial species, and people at a healthy weight could carry about 5,2-times more than those living with obesity. The results also showed a strong connection to diet, with people eating healthier diets having a higher microbiome score on this ranking.
Study Confirms High Bioavailability of NuAxon’s Curcumin
A new human clinical study confirms that NuAxon Bioscience’s BioTurm™ curcumin provides a 60 times higher bioavailability than standard curcumin with 95% standardized curcuminoids paired with piperine. The formulation achieves higher absorption by using a natural turmeric oil compound (ar-turmerone) instead of synthetic enhancers or high doses of piperine.
New Analysis Suggests Widespread Omega-3 Deficiency Worldwide
A new study showed that 76% of the global population is not consuming the recommended levels of omega-3, highlighting a major public health gap across all life stages. EPA and DHA intake remains below guidance, with researchers offering accessible, sustainable solutions such as enriched foods and supplements.
Nutgrass and Black Pepper Extract Could Support Weight Management
Sabinsa’s ingredients Cirpusins® nutgrass extract and BioPerine® black pepper extract might offer a natural alternative for weight management, according to a new study. Participants in the active group, supplementing both ingredients, experienced a 7,1% decrease in body weight and a 6,9% decrease in body mass index. Additionally, there was a reduction in total cholesterol, triglycerides, and Apolipoprotein B among the Cirpusins® + BioPerine® group compared to placebo.
Targeted Approach Might Be Needed for MVM Supplementation
An evaluation of findings from 19 meta-analyses suggested that multivitamin (MVM) supplementation could improve global cognition, episodic memory, and immediate recall in older or cognitively healthy adults, reduce psychological symptoms in healthy people, and lower systolic blood pressure in at-risk groups. On the other hand, MVM supplementation didn’t benefit all-cause mortality, COVID outcomes, or visual acuity, and it increased the risk of age-related macular degeneration progression. Researchers highlighted a need for consistency in the definition of MVM supplementation and variability in MVM effectiveness related to population, age, and health status.
